Filed in Category Pediatric Associates
Serotonin in autism and pediatric epilepsies.
Serotonin abnormalities have been reported in both autism and epilepsy. This association may provide insights into underlying mechanisms of these disorders because serotonin plays an important neurotrophic role during brain development-and there is evidence for abnormal cortical development in both autism and some forms of epilepsy. This review explores the hypothesis that an early disturbance in the serotonin system affects cortical development and the development of thalamocortical innervation, and is a potential mechanism, common to autism and pediatric epilepsies associated with cortical dysplasia. An argument is made that cortical malformation leads to abnormalities of thalamocortical connectivity, and that serotonin plays a critical role in this process. Finally, a role for altered metabloism of the serotonin precursur, tryptophan, in both epilepsy and autism is discussed.
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If you really want to get an accurate answer to this question contact a neurologist that is specially trained with regards to epilepsy issues, an epileptologist.
The data that you refer to in your question seems to be dealing with the formative period of the brain during childhood, I don’t think it applies to the adult brain.